tangled synapses



How Neuroscience & Resilience Overcome Depression

“The impaired, distorted ‘reality’ I am accustomed to experiencing just showed up. As has been its habit over the last six years my depression episode has taken on a life of its own. It usually lasts for about two or three hours during which feelings of powerlessness, a sense of discomfort and unreality take over- as if I am not here, yet nowhere- but wanting to be somewhere. Such confusion dominates the mind. A feeling that you do not exist as a human being; yet you breathe. You look but you do not see, you do not want to be but you are. You try desperately to feel in the present but it is as if you are leaving the scene of life, you are being taken away from reality, indeed from the world. Of course, you hate it, you really hate these feelings. A lot of thoughts and emotions come to mind. The most fervent one is that this torture ends right here, right now. But it does not. Time, then becomes your master. You feel that time never passes. Seconds, minutes, hours, and days become eternal. Agony, yes, agony is the best word to describe this. You give up on yourself, you give up on life, you care about nothing and you doubt anyone cares about you...”
 
The above is what a depressed person experiences day in and day out, however, this does not need to be.
 
 
The Tangled Synapses book written by Neuroscience Researcher Ignacio Sanabria, M.Ed., offers the most up to date research findings in the science behind of diagnosing, treating and preventing mental disorders such as depression. The Tangled Synapses book delves into the neuroscience and the resilience behind depression in search of effective recovery strategies. It introduces the depressed to the neurophysiobiology, neuroscience and resilience behind depression. After detailing why and how these disorders develop Sanabria explains existing theories and treatments for depression. Achieving his zero states as the ultimate life reward is what this book is all about. Readers follow the organic development of his hypothesis through practical application.
 
Depression is a very disabling mental disorder preventing the depressed from carrying on a normal life. According to the National Institutes of Mental Health, between 20%-40% of the US population will at some point in life develop depression. However this need not be the case as depression is a fully preventable disorder if detected in a timely manner.
 
The human body is a “biological machine with consciousness” and as such it obeys the laws of biology and is prone to malfunction. This biological malfunction is translated into disease, depression among the many possible. Depression would most likely develop as a result of genetic predisposition for the disorder in addition to dysfunctional interactions between the individual’s internal and external environments sustained over longer periods. This dysfunctionality compromise normal function of some or all of the 20 brain systems believed to be involved in depression such as: signaling systems, first messenger systems, second messenger systems, neuropeptides, prefrontal cortex, thalamus, LAPH axis, hypothalamus, nucleus accumbens, amygdala, hippocampus, pineal gland, insula, vagus nerve, thymus, regional cerebral blood flow, blood derivate neurotrophic factor, glucose metabolism, DHEA, CREB cycle, etc.
 
In TANGLED SYNAPSES Ignacio Sanabria bravely shares his ordeal with depression from several failed suicide attempts to transformative lifestyle changes he enacted in an effort to overcome depression. Sanabria refused to live under the shackles and limits of his diagnosis. His self developed therapy against this crippling disorder forced him to face it, confront underlying issues that allowed depression to fester under the surface during all those years, and finally beat it.
 
 
The book addresses the unspoken shame and fear that accompany depression with frankness and wit. In order to determine what ‘changes’ would improve his condition Sanabria embarked on a meaningful intellectual journey into research on the subject.
 
Mixing neuroscience with resilience Sanabria developed a workable blueprint of needed changes for healing. The main crux of these changes involved balancing his dysfunctional 3 daily life cycles - rest/activity, sleep/wake and diet/metabolism. These detailed changes were backed up by a health program for the body and mind aimed at restoring balance in the above mentioned brain systems.
 
At the core of his treatment was the miracle of water. Sanabria’s research found an unusual connection between healing and natural hot springs baths. In addition to traditional Cognitive Behavior Therapy, homeopathic compounds, exercise and diet regimes, acupuncture, and prescription medication, Sanabria’s open mindedness and determination helped him restore balance to his brain chemistry. This restoration was made possible by implementing a functional belief system that allowed him to carry through.
 
He hopes his hard won lessons might help or inspire any one of the millions of Americans currently suffering from or predicted to endure depression. Depression is a fully preventable disorder if detected in a timely manner. The best treatment against depression is to avoid develop it in the first place.
 
Order it online at an introductory price of $8.95.
 
 
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Printed copies will be available within 3 weeks. To reserve you copy, please email us at; tangled@tangledsynapses.com
 
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